Domperidone & ranitidine increase- baby going wacky??

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Permalink Reply by Gillian D on January 27, 2012 at 7:05

Noah was put back on domperidone recently and it made him very agitated and almost hyper. Followed by a massive crash at bedtime where he became hysterical. 

Gastro paed agreed it was the domperidone so possibly that is affecting Lily. If you want to keep givin her it maybe trying increasing the dosage from your original dose to the new dose over the space of a week and see if that helps her accept the new dosage. 
x

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Permalink Reply by Alison C on January 27, 2012 at 8:03

Thanks Gillian. Im damned with it and without it! She cant cope without it and is bugged with it. *SIGH* If you dont mind me asking did your Paed say that the irritability can subside after a while, after theyve become used to the dose? x

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Permalink Reply by Gillian D on January 27, 2012 at 8:09

He said no and agreed we shouldn't use it, but for us we weren't upping the dose we were just starting it. 

If Lily has been ok on it previously maybe a slow increase to the new dose will let her tolerate it. 
xx

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Permalink Reply by Alison C on January 27, 2012 at 22:01

Thanks Gillian , shes seems a little better today, so Im hoping she does settle. We had a bad night last night and it took ages to settle her each time. I should know over the next couple of days whether it is the domperidone. Ive downed it a bit and plan to increased slowly. Fingers crossed xx

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Permalink Reply by Lara Gent-Grant on January 28, 2012 at 19:15

Hi Alison, my Lo is also on Ranitidine and Domperidone. 1ml Ranitidine x 3 daily and 2 Ml Domperidone x 3 daily. He is constantly on the go, needs constant distractions and cries a help of a lot. He never seems relaxed in the day like a normal baby. its so tiring and I feel so Sorry for him. Maybe it is the meds as well as reflux. Really don't like the Domperidone, its given him a bad tummy.

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Permalink Reply by Jenny B on January 28, 2012 at 20:28

My LO reacts badly to the medications. We gave up the Gaviscon and ranitidine and when they wanted to up the omeprazole I decided no more of that either. It's been just over two weeks now and he's no worse off the medication than when he was on it. No better either, but I'm really hesitant now to try any more meds, the side effects are as bad as the reflux! 

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Permalink Reply by Alison C on January 31, 2012 at 7:43

Hi all,

Well good news, after a few days, Lily seems to have settled on the higher dose. I hate domperidone, but she just cant cope without it. For the first time ever, its been helping her bowels a little, so thats a positive. Still a bit agitated, needs constant distractions and her sleeping has gone a bit haywire, but deffo helped improve her reflux a little at night. She only woke once, which is a miracle! Cant wait til shes running about, in the hope that the extra movement gets her bowel moving/reflux knocked in the head.x

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